Acetaminophen Induces Mitochondrial Permeability Transition in Rats Without Causing Necrotic Liver Damage

Acetaminophen Induces Mitochondrial Permeability Transition in Rats Without Causing Necrotic Liver Damage

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Mitochondrial Permeability Transition (MPT) is reported as the mechanism of acetaminophen induced hepatic damage, however, rat models are resistant to acetaminophen induced toxicity. Theoccurences and degree of mitochondrial permeability transition after treatmnet with 400 mg/kg of acetaminophen in albino Wistar rats were assessed. Animals were randomly distributed into seven groups; control,...
 
Published at Journal of Biological Sciences
Volume 16
Pages 22-29
Published in 2016
 
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Oluwatobi Samuel Adegbite, Wisdom Oluwayemi Iyanda-Joel, Yetunde Ifeoma Akinsanya, Babafemi Nsikan Aka, Princessca Anulika Mogbo, Omolara Faith Yakubu, Blessing Oluwatosin Oladipo, Blessing Ariyo Afolabi, Ayobami Jahdahunsi Kukoyi, Benjamin Olusola Omiyale, Alex Emmacume Iyoha and Emmanuel Ndubuisi Maduagwu
Yakubu Omolara » PhD Biochemistry (2018). Covenant University MSc Biochemistry (2011). University of Ibadan BSc Biochemistry (2007). Ladoke Akintola University of Technology, Ogbomoso view full profile
Yakubu Omolara
 
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