Alterations of Genes Involved in Apoptosis and Epigenetic Modulation Associated with Gatifloxacin-Induced Oxidative Stress in Rat Liver

Alterations of Genes Involved in Apoptosis and Epigenetic Modulation Associated with Gatifloxacin-Induced Oxidative Stress in Rat Liver

Gatifloxacin is a fourth-generation fluoroquinolone that induces oxidative stress in the liver. Hence, this study investigated the alterations in the expression of genes involved in epigenetics and apoptosis associated with gatifloxacin-induced oxidative stress in rat liver. To achieve this, adult rats were exposed to oral doses (10 mg/kg, 20 mg/kg, 40 mg/kg and 80 mg/kg) of gatifloxacin for...
 
Published at Biomedical and Pharmacology Journal
Volume 11
Issue 1
Pages 583-591
Published in 2018
 
 
visit (http://biomedpharmajournal.org/vol11no1/alterations-of-genes-involved-in-apoptosis-and-epigenetic-modulation-associated-with-gatifloxacin-induced-oxidative-stress-in-rat-liver/)
 
 
Solomon Oladapo Rotimi, Iyanuoluwa Temitayo Olugbemi and Oluwakemi Anuoluwapo Rotimi
Rotimi Oluwakemi
 
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