Therapeutic Efficacies of Artemisinin-Based Combination Therapies in Nigerian Children with Uncomplicated Falciparum Malaria during Five Years of Adoption as Firs...

Therapeutic Efficacies of Artemisinin-Based Combination Therapies in Nigerian Children with Uncomplicated Falciparum Malaria during Five Years of Adoption as First-Line Treatments

~ D804314920ce239a9364a0382725eb5b.200x200
The therapeutic efficacies of 3-day regimens of artesunate-amodiaquine and artemether-lumefantrine during 5 years of adoption as first-line treatments were evaluated in 811 ≤ 12-year-old malarious children. Compared with artemether-lumefantrine, amodiaquine-artesunate significantly reduced the proportion of children with fever and parasitemia 1 day after treatment (day 1; P < 0.008 for...
 
Published at American Journal of Tropical Medicine and Hygiene
Volume 84
Issue 6
Pages 936-943
 
Download 644.75 kB
 
 
 
Gbotosho G. O., Sowunmi A., Happi C. T., Okuboyejo T. M.
Dokunmu Titilope » Titilope Dokunmu is a researcher in the Department of Biochemistry, where she teaches basic biomedical sciences, biochemistry, molecular biology and pharmacology. She is a multidisciplinary scientist with expertise in biochemistry, cell culture, molecular biology, genomics and experimental therapeutics. Her research focus is on disease mechanisms and dynamics. Her research interest is on... view full profile
Dokunmu Titilope
 
Other publications by this author (view profile)
 
 
Early Changes in Plasmodium falciparum Asexual and Sexual Populations in Children with Acute Infections Following Treatment with Artemisinin-Based Combination Drugs
 
Recrudescent Plasmodium falciparum infections in children in an endemic area following artemisinin-based combination treatments: Implications for disease control
 
Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children
 
Efficacy of Artemisinin-Based Combination Treatments of Uncomplicated Falciparum Malaria in Under-Five-Year-Old Nigerian Children
 
Fall in Hematocrit per 1000 Parasites Cleared From Peripheral Blood: A Simple Method for Estimating Drug-Related Fall in Hematocrit After Treatment of Malaria Infections
 
Oral Artesunate–Amodiaquine and Artemether–Lumefantrine in the Treatment of Uncomplicated Hyperparasitaemic Plasmodium falciparum Malaria in Children
 
A Simple Dose Regimen of Artesunate and Amodiaquine Based on Arm Span- or Age Range for Childhood Falciparum Malaria: A Preliminary Evaluation
 
Use of area under the curve to evaluate the effects of antimalarial drugs on malaria associated anemia after treatment
 
Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children
 
Therapeutic Efficacy and Effects of Artemether-lumefantrine and Artesunate-amodiaquine Coformulated or Copackaged on Malaria-Associated Anemia in Children with Uncomplicated Plasmodium falciparum Malaria in Southwest Nigeria
 
Plasmodium falciparum gametocyte carriage, sex ratios and asexual parasite rates in Nigerian children before and after a treatment protocol policy change instituting the use of artemisinin-based combination therapies
 
Plasmodium falciparum gametocyte carriage, emergence, clearance and population sex ratios in anaemic and non-anaemic malarious children
 
Early variations in Plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance
 
Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children
 
Therapeutic Efficacy and Effects of Artesunate-Mefloquine and Mefloquine Alone on Malaria-Associated Anemia in Children with Uncomplicated Plasmodium falciparum Malaria in Southwest Nigeria
 
Ex-vivo response of Plasmodium falciparum to dihydroartemisinin in an area of Ota South-west Nigeria
 
Artemisinin-induced delayed hemolysis after administration of artesunate and artesunate-amodiaquine in malaria-free Wistar rats
 
Cardiovascular Risk Factors in a Suburban Community in Nigeria
 
Plasmodium falciparum hyperparasitaemia in Nigerian children: epidemiology, clinical characteristics, and therapeutic responses to oral artemisinin-based combination treatments
 
Efficiency of histidine rich protein II-based rapid diagnostic tests for monitoring malaria transmission intensities in an endemic area
 
Frequencies of Plasmodium falciparum gene mutations in asymptomatic infection: Evaluating malaria transmission reduction in an endemic area
 
Hepatoprotective Potential and Histological Studies of Effects of Celosia Argentea L. on Paracetamol-Induced Liver Damage
 
A review on healthcare schemes in Nigeria: A case of Corona Virus pandemic
 
Asymptomatic malaria infections and Pfmdr1 mutations in an endemic area of Nigeria
 
New Insights into the Link between Melanoma and Thyroid Cancer: Role of Nucleocytoplasmic Trafficking
 
Hidden in plain sight: The effects of BCG vaccination in COVID-19 pandemic
 
Protective Effects of Caffeine and Artemisinin against Initiation of Breast Tumour in 7, 12-Dimethylbenzanthracene treated Albino Rats
 
Dataset on analysis of quality of health and social insurance subscription in different socio-economic class of workers in selected areas in southwest Nigeria