Analysis of the functional consequences of a single nucleotide polymorphisms in CYP3A4 gene to prostate cancer in men of African ancestry.

Analysis of the functional consequences of a single nucleotide polymorphisms in CYP3A4 gene to prostate cancer in men of African ancestry.

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Prostate cancer (CaP) is the leading cause of cancer death among black men and its pathogenesis is linked to testosterone metabolism. CYP3A4 deactivates testosterone and the polymorphisms of its gene are known to alter testosterone metabolism. In this study, computational techniques were used to investigate effects of non-synonymous single nucleotide polymorphisms (nsSNPs) in the CYP3A4 in...
 
Published at Proceedings of the American Association of Cancer Research (AACR)
Volume 59
Issue Part A: Abstracts 1 - 3027
Pages #403
Published in 2018
 
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visit (https://books.google.com.ng/books?id=xPBUDwAAQBAJ&lpg=PT479&ots=aC4KbHfkf8&dq=chinedu%20nwodo&pg=PT479#v=onepage&q&f=true 59)
 
 
Rotimi S.O., Ogo C.N., Ogunlana O.O., Shalom Nwodo Chinedu, Akinremi T, Fatiregun O., Buraimoh F., Alabi A., Tijani K., Salako A., Omonisi E., Agaba R., and Odedina F.
Chinedu Shalom » Shalom Nwodo Chinedu, a Professor of Biochemistry and Molecular Biology, is a faculty in the Department of Biochemistry, College of Science and Technology, Covenant University, Ota, Nigeria. Professor Chinedu is a seasoned academic, researcher and University administrator. He has been actively engaged in University education since 1992. He is the immediate past Director of the African... view full profile
Chinedu Shalom
 
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