Synthesis and evaluation of antimicrobial activity of phenyl and furan-2-yl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one and their hydrazone precursors

Synthesis and evaluation of antimicrobial activity of phenyl and furan-2-yl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one and their hydrazone precursors

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A variety of 1-(s-phenyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one (3a-3h) and 1-(s-furan-2-yl)-[1,2,4]triazolo[4,3- a]quinoxalin-4(5H)-one (5a-d) were synthesized from thermal annelation of corresponding hydrazones (2a-h) and (4a-d) respectively in the presence of ethylene glycol which is a high boiling solvent. The structures of the compounds prepared were confirmed by analytical and...
 
Published at Canadian Journal of Pure and Applied Sciences
Volume 3
Issue 3
Pages 983-992
Published in 2009
 
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Ajani, O.O. and Nwinyi, O.C.
AJANI OLAYINKA OYEWALE » Prof. Olayinka Oyewale AJANI is an expeditious chemist who has distinguished himself both as a seasoned industrialist and a prolific researcher in the academic world especially in the area of Organic Synthesis and Medicinal Chemistry. He obtained his Master’s degree in Chemistry in 2006 from Obafemi Awolowo University, Ile-ife, Osun State, Nigeria. In 2012, Ajani O.O. obtained his Doctoral... view full profile
AJANI OLAYINKA OYEWALE
 
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