Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide biological properties and diverse therapeutic applications in medicinal research. They are complementary in shapes and charges to numerous biomolecules they interact with, thereby resulting in increased binding affinity. The pharmacokinetic properties of drugs bearing quinoxaline cores have shown them to be...
 
Published at European Journal of Medicinal Chemistry
Volume 85
Pages 688-715
Published in 2014
 
 
visit (http://dx.doi.org/10.1016/j.ejmech.2014.08.034)
 
 
Ajani, O.O.
AJANI OLAYINKA OYEWALE » Prof. Olayinka Oyewale AJANI is an expeditious chemist who has distinguished himself both as a seasoned industrialist and a prolific researcher in the academic world especially in the area of Organic Synthesis and Medicinal Chemistry. He obtained his Master’s degree in Chemistry in 2006 from Obafemi Awolowo University, Ile-ife, Osun State, Nigeria. In 2012, Ajani O.O. obtained his Doctoral... view full profile
AJANI OLAYINKA OYEWALE
 
Other publications by this author (view profile)
 
 
Room temperature synthesis and antibacterial activity of new sulfonamides containing N,N-diethyl-substituted amido moieties
 
Facile synthesis and characterization of substituted pyrimidin-2(1H)-ones and their chalcone precursors.
 
Towards the conversion of carbohydrate biomass feedstocks to biofuels via hydroxylmethylfurfural
 
Eco-friendly room temperature synthesis in aqueous medium: An expeditious approach to new α-tolylsulfonamides bearing N,N-diethyl amide moieties
 
Functionalized 1,4-benzothiazine: A versatile scaffold with diverse biological properties
 
Adsorption behaviour of pyrazolo[3,4-b]pyridine on corrosion of stainless steel in HCl solutions
 
Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives
 
Microwave assisted synthesis and evaluation of antimicrobial activity of 3-{3-(s-aryl and s-heteroaromatic) acryloyl}-2H-chromen-2-one derivatives
 
Histological studies of brewery spent grains in dietary protein formulation in donryu rats
 
Improvement of nutritive value of sorghum ogi fortified with Pawpaw (Carica papaya L.)
 
Synthesis and antibacterial activity of some pyrazol-1-ylquinoxalin-2(1H)-one derivatives
 
Synthesis and evaluation of antimicrobial activity of phenyl and furan-2-yl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one and their hydrazone precursors
 
Comparative study of microwave assisted and conventional synthesis of novel 2- quinoxalinone-3-hydrazone derivatives and its spectroscopic properties
 
Antibacterial effects of extracts of Ocimum gratissimum and piper guineense on Escherichia coli and Staphylococcus aureus
 
Physical characterisation of some honey samples from North-Central Nigeria
 
Evaluation of antibacterial activity of Pisidium guajava and Gongronema latifolium
 
Synthesis, physical properties, antimicrobial potentials of some mixed antibiotics complexed with transition metals and their effect on alkaline phosphatase activities of selected rat tissues
 
Fe(III) and Co(II) complexes of mixed antibiotics: synthesis, characterization, antimicrobial potential and their effect on alkaline phosphatase activities of selected rat tissues
 
Synthesis, characterization, antimicrobial activity and toxicology study of some metal complexes of mixed antibiotics
 
Identification and Clinical Relevance of Gram-Positive Spore Formers
 
Cu(II) and Fe(III) complexes of sulphadoxine mixed with pyramethamine: Synthesis, characterization, antimicrobial and toxicology study
 
Synthesis and Spectroscopic Study of Naphtholic and Phenolic Azo Dyes
 
Synthesis and Antibacterial Activity of N,N-Diethyl-3-substituted-2- (4-methyl-phenylsulfonamido)alkanamides and their Arylsulfonamide Precursors
 
Synthesis and antibacterial activity of N,N-diethylamide bearing benzene sulfonamide derivatives.
 
Comparative Study of the Antibacterial Activity of N, N-Diethylamido Substituted p-Toluenesulfonamides to their α-Toluenesulfonamide Counterparts
 
Exploration of the chemistry and biological properties of pyrimidine as a privileged pharmacophore in therapeutic
 
Tandem synthesis of some low and high indexed monometallic nanoparticles in polyols, poly(vinylpyrrolidone), trisodium citrate and dodecanethiol matrices.
 
Expeditious synthesis and spectroscopic characterization of 2-methyl-3-substituted-quinazolin-4(3H)-one derivatives
 
Effect of polyol on multiple ligand capped silver alloyed nanobimetallic particles in tri-n-octylphosphine oxide and oleic acid matrices
 
Quinazoline pharmacophore in therapeutic medicine
 
Preliminary studies on the seed oil of Caryota mitis: Proximate composition, phytochemical screening and evaluation of antimicrobial activity
 
Functionalized benzimidazole scaffolds: privileged heterocycle for drug design in therapeutic medicine
 
Characterization, proximate composition and evaluation of antimicrobial activity of seed oil of Bauhinia tomentosa
 
Facile synthesis, characterization and antimicrobial activity of 2-alkanamino benzimidazole derivatives
 
Proximate composition, structural characterization and phytochemical screening of the seed oil of Adenanthera pavonina linn
 
Microwave assisted synthesis and antimicrobial potential of quinoline-based 4-hydrazide-hydrazone derivatives
 
Modeling and synthesis of Ag and Ag/Ni allied bimetallic nanoparticles by green method: Optical and biological properties.
 
Room temperature phyto-synthesis of Ag/Co bimetallic nanoparticles using aqueous leaf extract of Canna indica
 
Facile Synthesis and Characterization of New 2,3-Disubstituted Benzimidazole Derivatives