Comparative Study of the Antibacterial Activity of N, N-Diethylamido Substituted p-Toluenesulfonamides to their α-Toluenesulfonamide Counterparts

Comparative Study of the Antibacterial Activity of N, N-Diethylamido Substituted p-Toluenesulfonamides to their α-Toluenesulfonamide Counterparts

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Reaction of p-toluenesulfonyl chloride with amino acids gave sulfonamides p-T1a-k which upon amidation afforded p-T2a-k. Similarly, treatment involving α-toluenesulfonyl chloride and amino acids afforded the sulfonamides α-T1a-k. These two classes of sulfonamides were synthetically modified at their COOH end position to achieve N,N-diethylamido substituted p-toluenesulfonamides p-T2a-k and...
 
Published at Pakistan Journal of Biological Sciences
Volume 18
Issue 4
Pages 166-172
Published in 2015
 
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visit (http://dx.doi.org/10.3923/pjbs.2015.166.172)
 
 
Ajani O.O., Familoni O.B., Aderohunmu D.V., Ogunniran K.O., Adekoya J.A., Olanrewaju I.O.
AJANI OLAYINKA OYEWALE » Prof. Olayinka Oyewale AJANI is an expeditious chemist who has distinguished himself both as a seasoned industrialist and a prolific researcher in the academic world especially in the area of Organic Synthesis and Medicinal Chemistry. He obtained his Master’s degree in Chemistry in 2006 from Obafemi Awolowo University, Ile-ife, Osun State, Nigeria. In 2012, Ajani O.O. obtained his Doctoral... view full profile
AJANI OLAYINKA OYEWALE
 
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